The name may lead you to believe that TDSSKiller kills the TDSS rootkit, but the product does much more simply because so many common rootkits are based on, or derived from, TDSS. The current version detects and removes SST, Pihar, ZeroAccess, Sinowal, Whistler, Phanta, Trup, Stoned, RLoader, Cmoser, and Cidox. Unlike most rootkit killers, this one runs in Windows.
To run the program, fill out the form on the TDSSKiller page, wait for Kaspersky to send you a download link. Download the program and run it -- no installer, just an EXE. If any rootkits are found, you’ll be given the opportunity to Delete/Cure, Copy to quarantine, or Skip each identified interloper.